Tatsuya Morimoto Selected Research

sarpogrelate

12/2021

The Selective Serotonin 2A Receptor Antagonist Sarpogrelate Prevents Cardiac Hypertrophy and Systolic Dysfunction via Inhibition of the ERK1/2-GATA4 Signaling Pathway.

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Tatsuya Morimoto Research Topics

Disease

35	Heart Failure 02/2024 - 01/2004
27	Hypertrophy 02/2024 - 03/2002
16	Cardiomegaly (Heart Hypertrophy) 05/2023 - 01/2004
11	Fibrosis (Cirrhosis) 03/2024 - 01/2011
11	Myocardial Infarction 12/2022 - 11/2004
5	Neoplasms (Cancer) 12/2022 - 03/2004
5	Heart Diseases (Heart Disease) 09/2022 - 01/2004
4	Cardiovascular Diseases (Cardiovascular Disease) 05/2023 - 01/2012
4	Coronary Artery Disease (Coronary Atherosclerosis) 04/2022 - 11/2010
4	Atherosclerosis 04/2022 - 01/2011
4	Obesity 01/2020 - 01/2011
3	Left Ventricular Dysfunction 12/2022 - 01/2015
3	Hypertension (High Blood Pressure) 07/2021 - 04/2010
3	Insulin Resistance 01/2020 - 02/2010
3	Inflammation (Inflammations) 07/2019 - 01/2007
3	Weight Gain 10/2018 - 11/2016
3	Hypercholesterolemia 12/2016 - 01/2007
2	Fatigue 02/2024 - 11/2022
2	Left Ventricular Hypertrophy (Ventricular Hypertrophy, Left) 07/2021 - 02/2021
2	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2020 - 02/2010
2	Glucose Intolerance 01/2019 - 01/2010
2	Abdominal Obesity 01/2018 - 11/2016
2	Dyslipidemias (Dyslipidemia) 01/2015 - 01/2011
1	Tobacco Use Disorder (Nicotine Dependence) 01/2024
1	Mental Disorders (Mental Disorder) 11/2022
1	Major Depressive Disorder (Major Depressive Disorders) 11/2022
1	Cardiotoxicity 01/2022
1	Dementia (Dementias) 01/2022
1	Periodontal Diseases (Periodontal Disease) 11/2021
1	Body Weight (Weight, Body) 01/2020
1	Chronic Renal Insufficiency 11/2019
1	Type 2 Diabetes Mellitus (MODY) 01/2019

Drug/Important Bio-Agent (IBA)

17	CurcuminIBA 09/2022 - 03/2008
12	Histone Acetyltransferases (Histone Acetyltransferase)IBA 05/2023 - 02/2006
10	Phenylephrine (Neo-Synephrine)FDA LinkGeneric 02/2024 - 09/2004
9	Proteins (Proteins, Gene)FDA Link 04/2022 - 05/2003
9	Transcription Factors (Transcription Factor)IBA 12/2016 - 05/2003
6	Histones (Histone)IBA 03/2024 - 01/2020
5	Messenger RNA (mRNA)IBA 02/2024 - 04/2010
5	oxidized low density lipoproteinIBA 01/2019 - 01/2011
4	Biomarkers (Surrogate Marker)IBA 01/2022 - 01/2007
4	Glucose (Dextrose)FDA LinkGeneric 01/2019 - 01/2010
3	AdipokinesIBA 04/2022 - 01/2018
3	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2022 - 03/2004
3	GATA4 Transcription FactorIBA 01/2022 - 03/2002
3	SaltsIBA 07/2021 - 03/2008
3	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 01/2021 - 01/2015
3	DNA (Deoxyribonucleic Acid)IBA 04/2008 - 02/2006
2	Atrial Natriuretic Factor (ANF)IBA 02/2024 - 11/2021
2	AngiopoietinsIBA 04/2022 - 04/2013
2	Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA 01/2022 - 02/2021
2	TeaIBA 11/2021 - 01/2020
2	zerumboneIBA 11/2021 - 02/2021
2	pitavastatin (itavastatin)FDA Link 01/2021 - 12/2016
2	Rosuvastatin Calcium (Crestor)FDA Link 01/2021 - 12/2016
2	Mitogen-Activated Protein Kinase 3IBA 11/2020 - 03/2002
2	PolyphenolsIBA 11/2020 - 01/2018
2	LipidsIBA 01/2020 - 01/2011
2	Triglycerides (Triacylglycerol)IBA 01/2020 - 01/2011
2	1,5- bis(3,5- bis(methoxymethoxy)phenyl)penta- 1,4- dien- 3- oneIBA 01/2020 - 12/2017
2	AcetyltransferasesIBA 01/2020 - 02/2006
2	Lipoproteins (Lipoprotein)IBA 11/2016 - 01/2016
2	LDL Lipoproteins (beta Lipoproteins)IBA 01/2016 - 01/2012
2	CyclinsIBA 01/2016 - 03/2010
2	SolventsIBA 01/2014 - 01/2011
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2011 - 02/2010
2	Hemoglobins (Hemoglobin)IBA 01/2011 - 01/2010
2	Endothelin-1 (Endothelin 1)IBA 11/2004 - 03/2002
1	GSK3235025IBA 03/2024
1	Arginine (L-Arginine)FDA Link 03/2024
1	imidazoleIBA 02/2024
1	AnserineIBA 02/2024
1	DipeptidesIBA 02/2024
1	Carbon MonoxideIBA 01/2024
1	PhytochemicalsIBA 05/2023
1	shogaolIBA 05/2023
1	auraptenIBA 12/2022
1	Yi-Gan SanIBA 11/2022
1	Capsules (Microcapsules)IBA 09/2022
1	Brain Natriuretic Peptide (Natrecor)FDA Link 09/2022
1	pyrazoleIBA 06/2022
1	AnthracyclinesIBA 01/2022
1	Docosahexaenoic AcidsIBA 01/2022
1	Eicosapentaenoic AcidIBA 01/2022
1	5-HT2A Serotonin Receptor (5 HT2A Receptor)IBA 12/2021
1	sarpogrelateIBA 12/2021
1	Platelet Aggregation Inhibitors (Antiplatelet Drugs)IBA 12/2021
1	CollagenIBA 11/2021
1	Metformin (Glucophage)FDA LinkGeneric 10/2021
1	Coenzyme A (CoA)IBA 01/2021
1	mangostinIBA 01/2021
1	Transforming Growth Factor beta (TGF-beta)IBA 01/2021
1	Carrier Proteins (Binding Protein)IBA 11/2020
1	Nicotinamide MononucleotideIBA 01/2020
1	SirtuinsIBA 01/2020
1	Catechin (Z 7300)IBA 01/2020
1	Cystatin CIBA 11/2019
1	Lysine (L-Lysine)FDA Link 01/2019

Therapy/Procedure

16	Therapeutics 02/2024 - 05/2007
2	Drug Therapy (Chemotherapy) 11/2022 - 01/2021